IRDye 800CW EGF Optical Probe, LI-COR

ИК-зонд (800 нм) "IRDye 800CW EGF Optical Probe ", связывающий рецептор эпидермального фактора роста (EGFR). Представляет собой флуоресцентно-меченый рекомбинантный эпидермальный фактор роста (EGF) человека.

IRDye 800CW EGF Optical Probe is a near-infrared (NIR) fluorescently-labeled recombinant human epidermal growth factor (EGF). This optical imaging agent is composed of a recombinant EGF polypeptide containing 54 amino acid residues (molecular weight = 6.2 kDa) conjugated to the LI-COR IRDye 800CW infrared dye.

In vivo assays of EGF binding have proven effective in monitoring specific solid tumor models that exhibit overexpression of EGFR.

Epidermal growth factor receptor (EGFR) is one of a family of receptor tyrosine kinases found on the surface of epithelial cells, to which EGF binds. Many types of cancer cells have abnormally high EGFR levels on the cell surface