IRDye 800CW BoneTag, LI-COR

ИК-зонд (800 нм) "IRDye 800CW BoneTag" для связывания с кальцием в костной ткани. Представляет собой хелатирующий агент, который связывается с кальцием в костях. Может применяться для исследования степени и процесса минерализации костной ткани.

IRDye 800CW BoneTag Optical Probe is a calcium-chelating compound conjugated to IRDye 800CW near-infrared dye.

Using IRDye NIR dyes extends fluorescence signal detection to the near-infrared fluorescent region of the spectrum without affecting the compound’s ability to function as a marker of the mineralization process.

Calcium-chelating compounds have been used effectively for the detection of bone mineralization, growth, and morphological changes, including tetracycline derivatives, xylenol orange, alizarin, calcein, and fluorescein. NIR-labeled pamidronate has also been successfully used for detection of arterial calcification in non-invasive optical imaging.