IRDye 800CW PEG Contrast Agent, LI-COR

Контрастирующий агент "IRDye 800CW PEG Contrast Agent" на основе полиэтиленгликоля (ПЭГ) с порами 25-60 кДа, с ИК меткой (800 нм). Неспецифический агент, накапливающийся в капиллярах раковых опухолей.

IRDye 800CW PEG Contrast Agent (25-60 kDa) is a non-specific imaging agent intended to exploit enhanced permeability and retention (EPR) in tumor biology.

EPR is a common characteristic of tumor vasculature. The vascular endothelium in the tumor microenvironment is often discontinuous, allowing molecules to diffuse into the surrounding tumor tissue.1, 2 In addition to EPR, the lymphatic drainage for these regions is poor.3 Hence, larger molecules tend to accumulate.